Keynote lectures

We have something you really want to see. These are our Keynote Lectures, the special talks held by our most prominent guests. Held offsite in outstanding locations, we will make sure you will have everything you need to enjoy your science.

All participants are welcome to our Keynotes without prior booking. The exact details will be available in early April. Check our homepage for updates.

Switches and Latches: The Control of Entry into Mitosis

Sir Tim Hunt
Winner of the 2001 Nobel Prize in Physiology or Medicine

Sir Tim Hunt was awarded the Nobel Prize in Physiology or Medicine for his discovery of cyclins, proteins that regulate cyclin-dependent-kinases and that proved to be of great importance for cell cycle control. The cyclin mechanism of cell division is fundamental to all living organisms (excluding bacteria) and the study of the process in simple organisms (such as sea urchin) helps shed light on the growth of tumors in humans.

The Expanding Universe of Oxygen Sensing: From Cancer Genetics to Clinical Applications

Mircea Ivan
Associate Professor of Medicine, Associate Professor of Microbiology and Immunology, Indiana University, USA

Mircea Ivan’s research focuses on oxygen sensing, in particular in the context of tumorigenesis and anti-cancer therapy. Dr. Ivan is the discoverer of cellular HIF-prolyl hydroxylase oxygen sensors (reported in 2001 in the journal Science) and is a co-owner of key patents for clinical applications associated with interfering with this pathway. More recently, his group identified a novel branch of hypoxic signaling, involving microRNAs and long noncoding transcripts that fine-tune tumor metabolism.

The Cost of Accuracy: Half of Brain Neurons in the Cerebellum and a Dialogue with the Cerebral Cortex?

Clément Léna
Neurophysiology of Brain Circuits, Institut de Biologie de l’Ecole Normale Superieure de Paris, France

Clément Léna is a neurophysiologist with a history of study of the central cholinergic and serotoninergic systems. Over the last decade, he has developped an interest in the network dynamics of the cerebellum and of associated structures. He has notably been the first to establish the existence of functional closed loops between the cerebellum and the cerebral cortex and the inferior olive. His work aims at understanding how the cerebellar circuitry contributes to the function of the forebrain. He will be joining us for one of our Keynote Lectures and will present his inquiries into the crucial functions of cerebello-cortical circuits.

The Role of Inhibition in Learning and Memory

Hannah Monyer
Director of the Department of Clinical Neurology at the University Hospital in Heidelberg, Germany; Leibniz Prize Winner in 2004

Hannah Monyer is a prominent researcher whose studies had a major impact in neuroscience. Her talk will explain the concept of inhibitory neurons that play a pivotal role in the generation of network-characteristic oscillations. Oscillatory activity in different frequency ranges has been proposed to be critical for a number of cognitive tasks, including object representation, learning and memory. The goal of her studies is to identify ‘key’ molecules in GABAergic interneurons that underlie oscillatory activity and that are involved in controlling synchronous firing.

Axonal Plasticity in Health and Disease

Mihai Moldovan
Associate Professor at Institute of Neuroscience and Pharmacology, Faculty of Health Sciences, University of Copenhagen, Denmark

Mihai Moldovan is a neurophysiologist, pioneering translational investigational methods for the study of nervous system excitability in health and disease. His contributions further the understanding of the relationship between electrical impulse conduction and neuronal survival in both peripheral neuropathy and the comatose brain. He described the persistent axonal membrane dysfunction with increased energy demands resulting from shortened internodal length in regenerated axons. More recently, he identified that in demyelinating peripheral nervous system disorders and aging there is a maladaptive dysregulation of axonal voltage-gated Na+ channel isoforms. This opens novel treatment possibilities for neurodegenerative disease like Charcot-Marie-Tooth and Multiple Sclerosis.

Interventional Cardiology in the Pediatric Population: An Update from International Experts

Eustaquio Onorato & Serban Balanescu
Pediatric Interventional Cardiologist at Humanitas Gavazzeni Hospital, Bergamo, Italy & Head of the Clinical and Interventional Cardiology Department at Monza Hospital, Bucharest, Romania

Combining technology, precision, and most of all, consideration towards patients, this modern domain offers a viable minimally-invasive alternative to open heart surgery, while minimising procedural trauma and hospital admission time. Find out all the latest on Pediatric Interventional Cardiology, straight from the experts.